Services · Process development and scale-up

Process development and scale-up in Thailand: from a lab batch to kilogram scale

When a molecule works at lab scale, we develop the process and scale it up with you, from lab batches to kilogram scale, so the route still holds as quantities grow.

We sign an NDA before you send confidential details: your own form or ours.

A certificate of analysis (CoA) is available on request.

Discuss scale-up All services

Illustration: three vessels growing from a lab batch to kilogram scale.

Process development and scale-up

Suits you if

  • Your route already works at lab scale
  • You need more than a lab batch, up to kilogram scale
  • You want the route to hold as quantities grow

Discuss scale-up

Scale

From a first answer to kilogram scale

Every project starts with a plain answer on feasibility and moves up only as far as it needs to, up to kilogram scale. We do not offer GMP manufacturing.

How far a project can go with CHON ChemicalFour steps, each larger than the last: feasibility, lab batch, gram scale and kilogram scale, then a stop line. We work up to kilogram scale and do not offer GMP manufacturing.1Feasibility2Lab batch3Gram scale4Kilogram scaleUp to kilogram scaleWe do not offer GMP manufacturingHow far a project can go with CHON ChemicalFour steps, each larger than the last: feasibility, lab batch, gram scale and kilogram scale, then a stop line. We work up to kilogram scale and do not offer GMP manufacturing.1 Feasibility2 Lab batch3 Gram scale4 Kilogram scaleUp to kilogram scaleWe do not offer GMP manufacturing
Four FreshTrap 0.03% 1-MCP sachets on a table.

Worked example

Our own project: 1-MCP, from route to sachet

FreshTrap shows the whole path on one molecule: high-purity 1-MCP, synthesised and verified in Thailand.

1-MCP (1-methyl­cyclopropene) is a gas, which makes it hard to handle. We synthesise it in a closed system and capture it in α-cyclodextrin powder; moisture releases it again. Every production batch has its structure confirmed by NMR and its content measured by GC-MS, and the finished sachets are tested side by side on real crops in our in-house trials.

Registration with Thailand's Department of Agriculture is in progress.

See FreshTrap

Limits

When we are not a fit

The limits that apply to every service (quantity, timeline, certifications and regulated manufacturing) are listed once, on our services page.

Services

Our other services

Service

Analytical verification by NMR and GC-MS

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Contact

Tell us what you’re working on

Discuss scale-up (up to kilogram scale)

A molecule that works at lab scale, needed in larger amounts, up to kilogram scale. Discuss scale-up

+66 2 448 6244+66 95 264 5626contact@chonchemical.com